Hands Off is a Mac security app from One Periodic Inc. that controls access to your network and storage devices by applications to help prevent programs from “phoning home”, stealing sensitive information, or installing malware on your computer. Hands Off monitors applications and uses notifications and configuration rules to control what they can access. You can choose among default presets for ease of use or more detailed configuration options. Rules can be applied to a single user or globally to the whole system, and you can make them temporary (until the application quits) or persistent. (See Hands Off basics for more information).
Hands Off 4.4.2 is priced at $49.99 (one user) for OS X 10.11 and up, with a free demo version available. The latest update brings support for macOS Catalina 10.15.3 and 10.15.4. (Older versions are available for earlier Mac systems.)